Publisher's Synopsis
This volume presents research advances that provide novel strategies for developing or accelerating both preventive and therapeutic efforts against HIV.;Addressing the most important long- and short-term issues, "AIDS Research Reviews: Volume 3": supplies a comprehensive analysis of two HIV viral proteins, Tat and Rev, that modulate gene expression; discusses possible strategies for attacking HIV at the transcriptional level; demonstrates the potential utility of feline immunodeficiency virus as a small-animal model for HIV pathogenesis and vaccine design; reviews models for HIV pathogenesis and suggests that HIV-induced AIDS may result from immunological consequences similar to those of graft-versus-host disease; details the fine specificity of the host immune response to HIV infection; examines the therapeutic potential of various combinations of antibodies; and focuses on the challenges of "vaccine development" related to mucosal immunity and describes new poxvirus vectors for vaccine design.;With over 1830 literature citations, figures, and tables, "AIDS Research Reviews: Volume 3" is for microbiologists and virologists; molecular and cell biologists; immunologists; hematologists; oncologists; infectious disease specialists; pharmacologists; medicinal chemists, biochemists, and biotechnologists; parasitologists; and pathologists.
